The Ultimate Guide To https://www.ceesdekker.net
The Ultimate Guide To https://www.ceesdekker.net
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‘Certainly, which is about ideal. I hunt for a Actual physical understanding of biological devices in a bottom-up way. I do think you can distinguish 3 strains of analysis in my team in the meanwhile. The first considerations chromosome framework: How does one obtain a metre-prolonged DNA polymer folded and organised in this kind of microscopic cell? We've got formulated visualisation procedures that permit us to review how, one example is, SMC proteins loop DNA (online video on Youtube) in order to Develop up chromosomes.
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[Laughs] ‘It absolutely was unquestionably a great risk! At the time, I had been very well informed that it could go Mistaken and that I could grow to be much less successful, but I just disregarded that. Curiosity has often been my strongest driving drive. And by chance all of it worked out.’
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
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Our analysis ranges through the biophysics of DNA to synthetic cells and over and above. Remember to have a look beneath in the spectrum of our existing tasks.
All parameters had been the identical for every panel With this online video, aside from the Original placement of the 6hb rod (shown in blue) within the nanopore. Simulations that terminated early on account of translocation of your rod through the pore cees dekker are marked by a grey background.
Studying DNA loop extrusion by SMC proteins for chromosome architecture with one-molecule assays.
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Bulk-floor coupling identifies the mechanistic relationship between Min-protein patterns in vivo and in vitro
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Nanoscientist Cees Dekker is undoubtedly an amiable and flamboyant gentleman who appears Significantly younger than the sixty two yrs he in fact is – trendy Eyeglasses, psychedelic shirt, partaking smile – but not 1 to squander time. He usually takes his time, but not more than required.
2008, initially observation of protein-coated DNA translocation by nanopores; fixed the origin with the electrophoretic pressure on DNA in nanopores; learned a big velocity raise of microtubules in electrical fields; uncovered an anomalous electro-hydrodynamic orientation of microtubules; and solved the origin of sound in carbon nanotubes in liquid
2004, discovery of new physics in translocation of DNA by nanopores; 1st experimental research of ions conduction in nanofluidic channels; to start with electrochemistry with particular person single-wall carbon nanotubes; STM detection and Charge of phonons in carbon nanotubes; 1st electrical docking of microtubules on kinesin-coated nanostructures; initial biophysics characterization of your mechanical Homes of double-stranded RNA; and very first single-molecule analyze of DNA translocation by a restriction-modification enzyme.